Silicon (or OSA) Incorporated into Hydroxyapatite Composite Biomaterial More Effective for Bone Repair


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Silicon (or OSA) Incorporated into Hydroxyapatite Composite Biomaterial More Effective for Bone Repair

Latest finding published in Journal Biomed Material Research B Applied Biomaterial 2009 July ; 90 (1) : 123 – 30 by researchers from the prestigious Cambridge University showed that Silicon as OSA stimulate the expression of type I – collagen in osteoblast-like cell structures and have demonstrated enhanced bioactivity of silicon-substituted hydroxyapatite (Si-HA) over pure HA.

In this study, the researchers found that silicon (OSA) substitution into HA affects the adhesion of human osteoblast-like cells (HOBs) in culture. In addition, metabolic activity and proliferation of HOBs were increased by supplementation of the growth medium with 30 microM silicon (OSA).
Comment:

Silicon (as OSA) has been shown to have important effects on skeletal development and repair. Hence the incorporation of silicon (OSA) into biomaterial composite for bone repair is not unexpected since the new material can lead to significant improvements in the bioactive performance of the HA composite.

Fundamentally, this new publication once again re-affirmed the bioactive function of OSA for improve bone health.

So regular consumption of diet with high Si (OSA) is strongly recommended to prevent bone deterioration. One source of natural rich OSA is Spritzer Natural Mineral Water.

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