Silicon Supplement (ch-OSA) may Benefit Bone Health


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Silicon Supplement (ch-OSA) may Benefit Bone Health

Results from a new clinical trial add to mounting evidence that choline-stabilzed orthosilicic (ch-OSA) supplementation supports physiological roles in bone health and type 1 collagen synthesis.

The study ttiled “ Choline-Stabilized Orthosilicic Acid Supplementation as an Adjunct to Calcium/Vitamin D3 Stimulates Markers of Bone Formation in Osteopenic Females : Aa Randomized, Placebo-Controlled Trial” published in BMC Musculoskeletal Disorders 2008 Jun 11 ; 9 : 85.

ProfessorT.D Spector, from St. Thomas Hospital in London led a research team that investigated the effect of silicon, delivered as ch-OSA, on markers of bone turnover and Bone Mineral Density (BMD) during a 12-month randomized, placebo-controlled trial, completed by 114 women with osteopenia or osteoporosis. Volunteers were divided into four groups, all of the women received 1000 mg of calcium and 800 IU of vitamin D3 each day.

Three of the groups also took supplements of either 3, 6, or 12 mg of elemented silicon as ch-OSA marketed as BioSil.
The study found the supplement added to the benefits of the calcium and vitamin D supplementation.

The researchers reported improvement to several markers of bone formation, especially procollagen Type I N – terminal propeptide (PINP).

These were significant improvements after 12 months in those people taking 6 and 12 mg of the supplement.

Although spinal BMD did not change significantly, subgroup analysis (81 women) showed that volunteers taking 6 gm of silicon per day, and whose femur T score was less than –1 at the start of the study, showed significant femoral neck BMD improvements.

The researchers concluded:-
“ This study suggests that combined therapy of ch-OSA plus Ca/Vit D3 is a safe, well tolerated treatment that has a potentially beneficial effect on bone turnover, especially bone collagen, and possibly femoral BMD, compared to Ca/Vit D3 alone”.

 

Comment:

Previously presented research suggests that ch-OSA build and maintain bone by regulating bone mineralization, helping to trigger the deposition of calcium and phosphate, reducing the number of osteoclasts (bone destroying cells) and increasing the number of osteoblasts (bone building cells).

Physiological concentrations of OSA were recently found to stimulate type 1 collagen synthesis in human osteoblast-like cells and another study found that ch-OSA partially prevented femoral bone loss in the ovariectomy rat model, a standard model for investigating postmenopausal osteoporosis. Furthermore, an epidermiological study indicates that higher dietary silicon intake ( > 25 mg per day) is associated with greater BMD in both men and pre-menopausal women.

In addition, improvements in type 1 skin collagen after supplementation with ch-OSA have been noted in an animal study. Two recent clinical trial confirms ch-OSA helps reduce the appearance of wrinkles, helps improve skin elasticity, hair and nails.

The improvement in skin parameters are likely a result of the regeneration of damaged collagen fibers or the synthesis of new ones.
The good news is that by consuming one litre of Spritzer Natural Mineral Water a day, a person may be able to obtain 35 mg of Silicon as OSA which would confer all the health benefits mentioned above.

So drink up. Drink Spritzer Natural Mineral Water for healthy bone, skin, hair and nails.

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